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Message: <blockquote data-quote="Shinneryfarmer" data-source="post: 4095710" data-attributes="member: 46291">A 22-250 has always been my go to for everything deer size and smaller up until 12 yrs ago. Mine has taken over 15 deer probably closer to 20, lost count. I agree with shot placement, proper bullet design is key. Never had a deer run more than 40 yds and that was a double lung shot. I use multiple calibers deer hunting today but if I want to put meat on the table I'm grabbing my 22-250.     I had friend borrow my 22-250 for his son to use to deer hunt. They took it out and shot it a little so he could get use to it. When they brought it back after his son got his buck my friend made the comment " You just don't aim at the deer with that gun, you pick which hair you want to hit." I was laughing and he stated " That is the most accurate gun I ever shot, it will stack then in the same hole".</blockquote>