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Message: <blockquote data-quote="okietom" data-source="post: 2311910" data-attributes="member: 18710">There can be enough difference in case volume to raise pressures even using .223 data in 5.56 cases. The 5.56 brass is usually thicker and has less volume for powder which could give higher pressures with the same charge weight.That said I have loaded mixed brass with the same .223 charge weights with no problems. There may have been pressure variations doing that. As long as the pressures were not to high it would be safe.Pressure variations can contribute to accuracy problems.</blockquote>