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Message: <blockquote data-quote="swampratt" data-source="post: 3753972" data-attributes="member: 15054">I usually back off the max load stated in the book when going to a mag primer.If you are at the minimum load and change primers you will be fine at least in my testing in 38-357 and 45.Then work your way up and watch for signs.I have changed primers with ball powder in .223 cases and seen  as much as 100 fps difference  between primers.When I tested the same primers with stick powder and in .223 there was not any more than 25fps difference.With that in mind different powders will absolutely act different when you begin trying different primers.Small primer 45 has been around for quite some time.</blockquote>