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The Water Cooler
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Dogs and Rattlesnakes
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<blockquote data-quote="OK Corgi Rancher" data-source="post: 4321663" data-attributes="member: 45773"><p>I looked into that in 2016 or thereabouts right after moving to Idaho. Rattlesnakes were plentiful where we lived. At the time we were quoted a cost of about $600 for the first year and $200 to $300 for the yearly shots. I don't know if it was something new and that accounted for the high cost or what. But we were also told they'd still need basically the same treatment if they were bit. I wasn't sure why go to the expense of the vaccine if they still needed the same treatment. The vet did say it would buy time to get the treatment.</p><p></p><p>I talked about it to the doc yesterday and he quoted me $25 per shot, two the first year. That's far more reasonable. He also said they might need the same treatment, though, but he thought it made treatment of a snakebite somewhat more effective. But he said that was just anecdotal and not supported by any studies.</p><p></p><p>I did read this: (source: <a href="https://www.snakebitefoundation.org/blog/2023/6/13/veterinary-experts-do-not-recommend-the-rattlesnake-vaccine" target="_blank">https://www.snakebitefoundation.org/blog/2023/6/13/veterinary-experts-do-not-recommend-the-rattlesnake-vaccine</a>)</p><p></p><p>The American Animal Hospital Association (AAHA) recently released a statement highlighting the lack of evidence of vaccine (toxoid) efficacy. <a href="https://www.aaha.org/wp-content/uploads/globalassets/02-guidelines/2022-aaha-canine-vaccination-guidelines/resources/2022-aaha-canine-vaccinations-guidelines.pdf?fbclid=IwZXh0bgNhZW0CMTAAAR2Bm6jm_uf8GFVl9XIZcOI_XgMo90m1mJfR9xmgYKUTEFeB2qoJ98fKvPk_aem_AVU5LGLf4lZ7vCplQZwpJY1OHcGGtnVY8T-G7RXi30fLUR4kBNZr5Rczqr1P00YTwGdkB_jwtp0_afPiJwZkecWU" target="_blank"> Read It Here on page 9 under Rattlesnake Toxoid..</a></p><p></p><p><strong>Key points from the AAHA’s statement:</strong></p><p></p><ol> <li data-xf-list-type="ol">There is <strong>NO</strong> published data supporting the efficacy of the vaccine in dogs.</li> <li data-xf-list-type="ol">In a study that was performed in mice, where mice were given 50-1,500 TIMES the dose of the toxoid given to dogs during routine vaccination, survival following exposure to snake venom was still not guaranteed, and some vaccinated mice actually died or required euthanasia earlier than unvaccinated mice exposed to the same amount of venom.</li> <li data-xf-list-type="ol">Adverse reactions, including anaphylaxis, have been reported in vaccinated dogs.</li> <li data-xf-list-type="ol">Though the manufacturers make claims of cross-protection (protection from envenomation by pit viper species other than the western diamondback rattlesnake, the species used in the production of the toxoid), there are no data to support this claim.</li> </ol><p></p><p></p><p></p><p>The vaccine did not prove effective in a retrospective study looking at 272 cases of rattlesnake envenomations in dogs. <a href="https://www.ncbi.nlm.nih.gov/pubmed/26341419" target="_blank">Read It Here.</a></p><p></p><p>Key findings from the study:</p><p></p><ol> <li data-xf-list-type="ol">There was no evidence that vaccination lessened morbidity or mortality.</li> <li data-xf-list-type="ol">No measurable benefit could be identified associated with rattlesnake vaccination.</li> </ol><p></p><p></p><p></p><p>Furthermore, the rattlesnake vaccine toxoid may predispose snakebitten dogs to anaphylaxis by providing the necessary sensitizing exposure to snake venom antigens. <a href="https://www.sciencedirect.com/science/article/abs/pii/S004101011730404X?fbclid=IwAR3_vbz8D7S9CjZthbzZCOgbcAZX4YBnuhUt0rEpjMODl3M_vdly6QwgsoE" target="_blank">Read It Here.</a></p><p></p><p>Key findings from the study:</p><p></p><ol> <li data-xf-list-type="ol">There are no peer-reviewed publications providing evidence of clinical efficacy in snakebitten dogs.</li> <li data-xf-list-type="ol">Anaphylaxis requires prior sensitization to an antigen; it is proposed that repeated vaccinations with the rattlesnake toxoid vaccine serve as a sensitization event to snake venom.</li> </ol></blockquote><p></p>
[QUOTE="OK Corgi Rancher, post: 4321663, member: 45773"] I looked into that in 2016 or thereabouts right after moving to Idaho. Rattlesnakes were plentiful where we lived. At the time we were quoted a cost of about $600 for the first year and $200 to $300 for the yearly shots. I don't know if it was something new and that accounted for the high cost or what. But we were also told they'd still need basically the same treatment if they were bit. I wasn't sure why go to the expense of the vaccine if they still needed the same treatment. The vet did say it would buy time to get the treatment. I talked about it to the doc yesterday and he quoted me $25 per shot, two the first year. That's far more reasonable. He also said they might need the same treatment, though, but he thought it made treatment of a snakebite somewhat more effective. But he said that was just anecdotal and not supported by any studies. I did read this: (source: [URL]https://www.snakebitefoundation.org/blog/2023/6/13/veterinary-experts-do-not-recommend-the-rattlesnake-vaccine[/URL]) The American Animal Hospital Association (AAHA) recently released a statement highlighting the lack of evidence of vaccine (toxoid) efficacy. [URL='https://www.aaha.org/wp-content/uploads/globalassets/02-guidelines/2022-aaha-canine-vaccination-guidelines/resources/2022-aaha-canine-vaccinations-guidelines.pdf?fbclid=IwZXh0bgNhZW0CMTAAAR2Bm6jm_uf8GFVl9XIZcOI_XgMo90m1mJfR9xmgYKUTEFeB2qoJ98fKvPk_aem_AVU5LGLf4lZ7vCplQZwpJY1OHcGGtnVY8T-G7RXi30fLUR4kBNZr5Rczqr1P00YTwGdkB_jwtp0_afPiJwZkecWU'] Read It Here on page 9 under Rattlesnake Toxoid..[/URL] [B]Key points from the AAHA’s statement:[/B] [LIST=1] [*]There is [B]NO[/B] published data supporting the efficacy of the vaccine in dogs. [*]In a study that was performed in mice, where mice were given 50-1,500 TIMES the dose of the toxoid given to dogs during routine vaccination, survival following exposure to snake venom was still not guaranteed, and some vaccinated mice actually died or required euthanasia earlier than unvaccinated mice exposed to the same amount of venom. [*]Adverse reactions, including anaphylaxis, have been reported in vaccinated dogs. [*]Though the manufacturers make claims of cross-protection (protection from envenomation by pit viper species other than the western diamondback rattlesnake, the species used in the production of the toxoid), there are no data to support this claim. [/LIST] The vaccine did not prove effective in a retrospective study looking at 272 cases of rattlesnake envenomations in dogs. [URL='https://www.ncbi.nlm.nih.gov/pubmed/26341419']Read It Here.[/URL] Key findings from the study: [LIST=1] [*]There was no evidence that vaccination lessened morbidity or mortality. [*]No measurable benefit could be identified associated with rattlesnake vaccination. [/LIST] Furthermore, the rattlesnake vaccine toxoid may predispose snakebitten dogs to anaphylaxis by providing the necessary sensitizing exposure to snake venom antigens. [URL='https://www.sciencedirect.com/science/article/abs/pii/S004101011730404X?fbclid=IwAR3_vbz8D7S9CjZthbzZCOgbcAZX4YBnuhUt0rEpjMODl3M_vdly6QwgsoE']Read It Here.[/URL] Key findings from the study: [LIST=1] [*]There are no peer-reviewed publications providing evidence of clinical efficacy in snakebitten dogs. [*]Anaphylaxis requires prior sensitization to an antigen; it is proposed that repeated vaccinations with the rattlesnake toxoid vaccine serve as a sensitization event to snake venom. [/LIST] [/QUOTE]
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