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Message: <blockquote data-quote="rhodesbe" data-source="post: 2023894" data-attributes="member: 2415">I use it Humulin R in my insulin pump.  You can buy it with no RX required at any Walmart for $25/vial.The difference between Humulin R/Novolin R and the 'log' insulins (ie: Humalog/Novolog) is how quickly they act to lower blood sugar, generally within 15 minutes.  For example, because I use an insulin pump, I only take one type of insulin.  The quicker it begins to be absorbed, the less time is required between eating something and taking insulin - resulting in a lower BG spike.  The 'R' insulins (R stands for Rapid) do not act as quickly, generally within 45 minutes.  However, despite the 'power curve' differences, they are equally as potent and I generally can exchange them 1:1.</blockquote>