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The Water Cooler
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Poll: Marijuana Law Reform
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<blockquote data-quote="_CY_" data-source="post: 2358822" data-attributes="member: 7629"><p>Tapping Medical Marijuanas Potential</p><p></p><p>Marijuana has been used medically, recreationally and spiritually for about 5,000 years. Known botanically as cannabis, it has been called a crude drug: marijuana contains more than 400 chemicals from 18 chemical families. More than 2,000 compounds are released when it is smoked, and as with tobacco, there are dangers in smoking it.</p><p></p><p>Medical marijuana clinics operate in 20 states and the District of Columbia, and its recreational use is now legal in Colorado and Washington. A Gallup poll conducted last month found that 58 percent of Americans support the legalization of marijuana.</p><p></p><p>Yet researchers have been able to do relatively little to test its most promising ingredients for biological activity, safety and side effects. The main reason is marijuanas classification by Congress in 1970 as an illegal Schedule I drug, defined as having a potential for abuse and addiction and no medical value.</p><p></p><p>American scientists seeking clarification of marijuanas medical usefulness have long been stymied by this draconian classification, usually reserved for street drugs like heroin with a high potential for abuse.</p><p></p><p>Dr. J. Michael Bostwick, a psychiatrist at the Mayo Clinic in Rochester, Minn., said the classification was primarily political and ignored more than 40 years of scientific research, which has shown that cellular receptors for marijuanas active ingredients are present throughout the body. Natural substances called cannabinoids bind to them to influence a wide range of body processes.</p><p></p><p>In a lengthy report entitled Blurred Boundaries: The Therapeutics and Politics of Medical Marijuana, published last year in Mayo Clinic Proceedings, Dr. Bostwick noted that the so-called endocannabinoid system has an impact on the autonomic nervous system, immune system, gastrointestinal tract, reproductive system, cardiovascular system and endocrine network.</p><p></p><p>There is evidence that several common disorders, including epilepsy, alcoholism and post-traumatic stress disorder, involve disruptions in the endocannabinoid system, suggesting that those patients might benefit from marijuana or its ingredients.</p><p></p><p>The strongest evidence for the health benefits of medical marijuana or its derivatives involves the treatment of chronic neuropathic pain and the spasticity caused by multiple sclerosis. Medical marijuana is widely recognized as effective against nausea and appetite loss caused by chemotherapy, although better treatments are now available. But preliminary research and anecdotal reports have suggested that marijuana might be useful in treating a number of other conditions, including irritable bowel syndrome, Crohns disease, glaucoma, migraine, cancer growth, abnormal heart rhythms, Alzheimers disease, fibromyalgia, incontinence, bacterial infections, osteoporosis, intense itching, Tourettes syndrome and sleep apnea.</p><p></p><p>Medical experts emphasize the need to reclassify marijuana as a Schedule II drug to facilitate rigorous scientific evaluation of the potential therapeutic benefits of cannabinoids and to determine the optimal dose and delivery route for conditions in which efficacy is established, Diane E. Hoffmann and Ellen Weber, legal experts at the University of Maryland, wrote in The New England Journal of Medicine.</p><p></p><p><a href="http://well.blogs.nytimes.com/2013/11/04/tapping-medical-marijuanas-potential/" target="_blank">http://well.blogs.nytimes.com/2013/11/04/tapping-medical-marijuanas-potential/</a></p></blockquote><p></p>
[QUOTE="_CY_, post: 2358822, member: 7629"] Tapping Medical Marijuanas Potential Marijuana has been used medically, recreationally and spiritually for about 5,000 years. Known botanically as cannabis, it has been called a crude drug: marijuana contains more than 400 chemicals from 18 chemical families. More than 2,000 compounds are released when it is smoked, and as with tobacco, there are dangers in smoking it. Medical marijuana clinics operate in 20 states and the District of Columbia, and its recreational use is now legal in Colorado and Washington. A Gallup poll conducted last month found that 58 percent of Americans support the legalization of marijuana. Yet researchers have been able to do relatively little to test its most promising ingredients for biological activity, safety and side effects. The main reason is marijuanas classification by Congress in 1970 as an illegal Schedule I drug, defined as having a potential for abuse and addiction and no medical value. American scientists seeking clarification of marijuanas medical usefulness have long been stymied by this draconian classification, usually reserved for street drugs like heroin with a high potential for abuse. Dr. J. Michael Bostwick, a psychiatrist at the Mayo Clinic in Rochester, Minn., said the classification was primarily political and ignored more than 40 years of scientific research, which has shown that cellular receptors for marijuanas active ingredients are present throughout the body. Natural substances called cannabinoids bind to them to influence a wide range of body processes. In a lengthy report entitled Blurred Boundaries: The Therapeutics and Politics of Medical Marijuana, published last year in Mayo Clinic Proceedings, Dr. Bostwick noted that the so-called endocannabinoid system has an impact on the autonomic nervous system, immune system, gastrointestinal tract, reproductive system, cardiovascular system and endocrine network. There is evidence that several common disorders, including epilepsy, alcoholism and post-traumatic stress disorder, involve disruptions in the endocannabinoid system, suggesting that those patients might benefit from marijuana or its ingredients. The strongest evidence for the health benefits of medical marijuana or its derivatives involves the treatment of chronic neuropathic pain and the spasticity caused by multiple sclerosis. Medical marijuana is widely recognized as effective against nausea and appetite loss caused by chemotherapy, although better treatments are now available. But preliminary research and anecdotal reports have suggested that marijuana might be useful in treating a number of other conditions, including irritable bowel syndrome, Crohns disease, glaucoma, migraine, cancer growth, abnormal heart rhythms, Alzheimers disease, fibromyalgia, incontinence, bacterial infections, osteoporosis, intense itching, Tourettes syndrome and sleep apnea. Medical experts emphasize the need to reclassify marijuana as a Schedule II drug to facilitate rigorous scientific evaluation of the potential therapeutic benefits of cannabinoids and to determine the optimal dose and delivery route for conditions in which efficacy is established, Diane E. Hoffmann and Ellen Weber, legal experts at the University of Maryland, wrote in The New England Journal of Medicine. [url]http://well.blogs.nytimes.com/2013/11/04/tapping-medical-marijuanas-potential/[/url] [/QUOTE]
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