Yep thats kind of what i do with my 41 mags. Stout load of the old Hornady 210 gr. for deer and lighter loads both lead and jacketed for shooting paper at the house.I quit building full-house magnums some time ago, but I did use H110 in my 44 mag loads. MPPs are important with H110 (I also understand W296 is the same stuff….), as is the minimum charge. I used Nosler 240 grain JHPs, which I thought were good-they were not! I had jacket separation (and hideous accuracy), within published powder charges. The cost of “magnum” capable bullets and not being much fun to shoot convinced me to buy the bear-killers and load fun target rounds at moderate velocities with my 45ACP powder.