I have never had a deer or elk complain when hit with a 223 or 22-250. Usually drops them. Minimal tracking. The 250 is like a laser beam.I have a good friend that is a biologist. Elk and whitetail are among the free range animals. When they are doing sampling for disease research he shoots a tack driving 22-250 with Barnes 50 grain TTSX. Pretty routine for 1 shot quick kills on deer and elk.
Does it mean it is perfect for everybody? Nope it doesn't. Some folks couldn't hit the ground with their hat if they had 5 chances.