I carry a picture of my ex mother-in-law...Common carrier and caliber is a key component. An ability to reach out and get deer at a longer range is necessary. Close action to remove the possum in my henhouse is also necessary. When I am hunting it is usually less than 100 yards unless it is elk or in a really wide open area with long lines of sight and deep backdrops.
Nothing is right for everything or everyone. Sometimes it takes multiple options. I carry rat shot in my 22 revolver for the rats and poisonous snakes. Works well.