On the rare occasion I carry IWB, I carry a full size 5" XD45 in a Crossbreed Supertuck at ~2-2:30. Never had a concealment issue, but after ~12 hours I would have an "XD" imprint in my side from the grip that would stay there through the next morning.
I'm not sure that I could put up with that. Of course, there's no way I could carry at that position either. Thanks for the reply Veg.