The 25-06 is my favorite do all caliber just ahead of the lil 243 but the ranges I hunt at these days I've stepped down to the 223, it's cheaper to shoot & handles my needs but if we're going to build another long range coyote/deer rifle 25-06 would be it for sureI have turned them inside out with my 25/06 a lot but seems like my Henry 22 does a fine job on them also.