I don't think so (from a steel-material expense standpoint), but from a strength/edge-retention standpoint, to be honest, as long as the steel has enough Carbon in it to heat treat it to a proper hardness, it will make a good enough blade for a folder (same can be said of a fixed-blade, but to me its more critical to get it right since fixed-blades tend to get used a little more harshly). You probably won't notice too much of a difference in an EDC folder if both blades are made from quality steel by good manufacturers who are using decent heat-treating/tempering.
The real trick is the tempering / cryo / Heat-treating and quality of the steel in the first place.
I wouldn't turn my nose up at any decent knife made from S30V. There are lots of good knife makers out there doing great things with S30V, 154-CM (154-CPM), SR-101, SR-77, etc... (Scrapyard and Swamp Rat are two companies using the SR-77/101 steels with good results).
Check out the Heat Treating section of this page:
http://www.scrapyardknives.com/tech.htm
Its Scrapyard Knife's explanation of how heat-treating / Tempering is one of the most fundamentally important parts of a steel's ability to perform as a knife-blade.
Thanks for the link. Do you have an opinion on the S30V Spyderco Native Looks like a nice slim knife around the same size as the mini grip.