I've killed a few deer and a hog with my Ruger 350 rem mag. Pretty unrated round, especially when reloaded with some 225gr ballistic tips. Remington didn't do the cartridge any favors by offering it in the model 600 and 660 first and it beat people up. Once it was offered in the model 700 it was too late imo. Barely made it into the 1970's when it was discontinued iirc.