I'd have to see your setup and see you shoot. You shouldn't have to re-establish anything..it's a 6.5 Grendel and not a .50. Could be too low, too high, high rings/mount and no riser, Comb too tall and low rings, etc. Could be just how you shoot, but IDK.I am having to re establish cheek weld after each shot unfortunately, I am shooting it cross arm style so after reading your comment I'm wondering if hold the forearm may help?