They will, she just may have to increase the flow rate a little to compensate for the lower FiO2 output (%). Probably need something like 3 liters per minute.2.5 Liters per Minute is the problem.
Home concentrator 2.5 Liters per minute (50 foot hose, locate in center of house)
Most portable concentrators are 2 liters per minute (burst) (OK for short periods of time)
E-Tank, keep in car (4 Hours at 2.5 6 Hours on 2.0)
Work a separate home concentrator or E-Tanks (Depends on Work conditions)
This is based on my Dad from 10 years ago.
A portable concentrator will not work for above 2.0 litters per minute. and she need 2.5 liters.
Things may have changes in the last few years.