Best to check with Ruger.
Last I got from them, since starting back up from Covid shutdown, they are not sending parts back. They are not fitting .45 ACP cylinders to .45 Colt.
You might could specify, but I know of 1 that was sent for repair (not trigger / hammer related) and they put the transfer bar in. Lawyers most likely had something to do it.
Things may change, as time goes on, but unmolested 3-screw are getting a lot of interest.
My 3, will not go back.
Haven't heard anything about .22s.
Truth! Best ask. I got mine back, but was awhile ago.